摘要妊娠期高血压疾病(hypertensive disorders in pregnancy)是妊娠期特有的疾病。该病严重影响母婴健康,是孕产妇和围产儿病率和病死率的主要原因。至今病因未明。从免疫学观点看,妊娠被认为是成功的自然同种异体移植,正常妊娠的维持有赖于胎儿母体间免疫平衡的建立和稳定,如这种平衡被打破,即可导致发生免疫排斥反应,
2Redmancw G, Sargenti L. Latest advances in understanding PreeclamPsia[J]. Science,2005,308(5728) :1592-1594. 被引量:1
3Sibai B,Dekker G. KuPherminc M. preeclampsia[J]. Lancet, 2005, 365(9461) :785-799. 被引量:1
4Merviel P, Carbillon L, ChaUier JC, et al. Pathophysiology of Preeclam Psia: links withlmplantation disorders[J]. European J Obstet Gynecol Reprod Biol, 2004,115(2) : 134-147. 被引量:1
5Greenwald R J, Freeman G J, Sharpe A H. The 137 family revisited [J]. AnnuRevlmmunol,2005, 23:515-5,t8. 被引量:1
6Steppich BA, Moog P,Matissek C,et al. Cytokine Profiles and T cell function in acute coronary syndromes [J] Atherosclerosis, 2007, 190(2), 443-451. 被引量:1
7D Souza M,Fontenot AP,Mack DG,et al. Programmed death 1 ex pression on HIV specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction[J]. J Immunol, 2007, 179 (3) : 1979-1987. 被引量:1
5Kelemen K,Paldi A,Tinnberg H,et al.Early recognition of preg-nancy by the maternal immune system.Am J Reprod Immunol,1998,39:351-355. 被引量:1
6Arikan DC,Aral M,Coskun A,et al.Plasma IL-4,IL-8,IL-12,interferon-γand CRP levels in pregnant women with preeclamp-sia,and their relation with severity of disease and fetal birthweight.J Matern Fetal Neonatal Med,2012,[Epub ahead ofprint] . 被引量:1
7Darmochwal-Kolarz D,Rolinski J,Leszczynska-Goarzelak B,etal.The expressions of intracellular cytokines in the lymphocytesof preeclamptic patients.Am J Reprod Immunol,2002 Dec,48:381-386. 被引量:1
8Sakai M,Tsuda H,Tanebe K et al.Interleukin-12 secretion bype-ripheral blood mononuclear cells is decreased in normal preg-nant subjects and increased in preeclamptic patients.Am J Rep-rod Immunol,2002,47:91-97. 被引量:1
9Guner S,Y i It S,Cet i Nm,et al.Evaluation of serum granulo-cyte colony.Stimulating factor levels in infants of preeclampticmothers.Turk J Pediatr,2007,49:55-60. 被引量:1
10Bersinger NA.Serum levels of macrophage colony stimulating,vascular endothelia,and placenta growth factor in relation to laterclinical onset of pre-eclampsia and a small-for-gestational agebirth.Am J Reprod Immunol,2005,54:77. 被引量:1