摘要
目的:分析首都医科大学附属北京佑安医院核苷类抗病毒药的应用情况,评价抗病毒药的临床应用,为临床合理用药提供参考。方法:利用医院HIS系统,调取我院2007—2009年核苷类抗病毒药的年消耗金额和用量,采用限定日剂量(DDD)方法,对用药频度(DDDs)及日均费用(DDC)等进行统计分析。结果:我院核苷类抗病毒药的应用呈现逐年增长趋势,其中以阿德福韦酯和恩替卡韦使用居多。结论:口服核苷类抗病毒药已成为抗慢性乙型肝炎病毒(HBV)治疗的主要手段,应进一步规范合理使用,优化治疗方案,降低耐药变异率。
OBJECTIVE：To analyze the utilization of nucleotide antiviral drugs in Beijing You’an hospital and evaluate their clinical use in order to provide references for clinical rational drug use.METHODS：Using hospital HIS system,the consumption sum and quantity of nucleotide antiviral drugs in our hospital during 2007-2009 period were retrieved for statistical analysis regarding the DDDs and the daily drug costs（DDC） by employing the method of defined daily dose（DDD）.RESULTS：The consumption of nucleotide antiviral drugs in our hospital increased year by year.Adefovir dipivoxil and Entecavir were the predominantly used antiviral drugs in our hospital.CONCLUSION：Oral nucleotide antiviral drugs have become the predominant anti-HBV therapy.Rational and standard use of which should be intensified and the therapeutic regimen should be optimized to reduce mutant resistance rate
出处
《中国医院用药评价与分析》
2011年第6期514-516,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
