摘要
目的评价三氧联合玻璃酸钠治疗膝骨性关节炎（KOA）的临床效果。方法选择膝骨性关节炎患者31例40膝，随机分为两组，每组20膝。实验组使用40μg／ml医用三氧行膝关节腔内注射，连续3周，继以玻璃酸钠注射，连续治疗3周；对照组行玻璃酸钠膝关节腔内注射，连续5周。比较两组治疗前后患者的VAS评分、关节活动度（ROM）、Lysholm关节功能评分变化情况和治疗效果。结果治疗后两组患者VAS、ROM和Lysholm关节功能总分均较治疗前明显改善（P〈0．05）；实验组患者关节肿胀、疼痛和跛行3项得分高于对照组（P（0．05），治疗优良率高于对照组（P〈0．05）。结论三氧40μg／ml联合玻璃酸钠膝关节腔内注射治疗KOA较单纯注射玻璃酸钠疗效显著。
Objective To evaluate the clinical effect of knee osteoarthritis （KOA） treated with intra-articular ozone and sodium hyaluronate. Methods Thirty-one patients, 40 knees,were randomly divided into two groups, 20 knees in each group. In experimental group,the patients were received intra-articular injection of medical ozone （40 tzg/ml） for 3 weeks, then followed by injection of sodium hyaluronate for 3 weeks. The patients in control group were injected sodium hyaluronate for 5 weeks. The range motion of knee joint,VAS,ROM score, and Lysholm score were evaluated and compared after treatment. Results The range of motion and joint function were improved significantly after treatment （P〈0.05）. In the experimental group, the score of joint swelling, pain, lameness and the excellent rate were significantly higher than that in the control group （P〈0. 05）. Conclusion The treatment of KOA using intra-articular ozone combined with sodium hyaluronate is a good method, and it also effectively reduce the consumption of sodium hyaluronate and the costs of the patients.
出处
《实用疼痛学杂志》
2011年第2期87-89,共3页
Pain Clinic Journal
基金
广西教育厅科研项目（桂教200911LX26）
关键词
三氧
玻璃酸钠
膝骨性关节炎
Ozone
Sodium Hyaluronate
Knee Osteoarthritis
