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炎性反应在肺癌发生中的作用 被引量:5

Studies on the Effects of Inflammatory Response During the Occurrence of Lung Cance
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摘要 炎症是具有血管系统的活体组织对损伤因子所发生的复杂的防御反应。炎症可以改变癌基因和抑制癌基因(包括蛋白质编码基因和非编码小分子RNA基因)的表达和转化,以促进细胞向恶性转变。肺癌是一种严重威胁人类健康与生命的恶性肿瘤,而炎性反应是导致肺癌发生的重要因素。现就炎性反应在肺癌发生中的促进作用综述国内外的研究进展。 Inflammation is the complex defense response of vascular living tissues to injury factors.Inflammation can change oncogenes and inhibit the expression and transformation of oncogenes(including protein-coding genes and non-coding miRNA genes),thus to promote malignant transformation of cells.Lung cancer is a kind of malignant tumor which severely threatens the health and life of human beings,while inflammatory response is an important factor that leads to the occurrence of lung cancer.The author hereby summarizes the progress of domestic and overseas studies on the promoting effects of inflammatory response during the occurrence of lung cancer.
出处 《医学综述》 2011年第12期1804-1805,共2页 Medical Recapitulate
关键词 炎症 肺肿瘤 抗肿瘤治疗 Inflammation Lung tumor Anti-tumor therapy
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