摘要
系统性红斑狼疮(SLE)是多基因遗传的自身免疫性疾病,发病机制十分复杂。遗传因素和环境因素共同导致了该病的发生。TNIP1被认为是SLE的一个新的易感基因,在免疫调节方面有重要作用。本文就SLE与TNIP1研究进展进行综述。
Systemic lupus erythematosus(SLE) is an polygenic inheritance autoimmune disease,and the pathogenesis is very complicated. Both genetic and environmental factors contribute to the development of SLE. TNIP1 is considered to be a new systemic lupus erythematosus susceptibility gene, and play a singnificant role in immune regulation. The correlation between SLE and TNIP1 was reviewed in this paper.
出处
《皮肤病与性病》
2011年第3期156-158,共3页
Dermatology and Venereology