摘要
目的:观察抗抑郁药路优泰(圣.约翰草提取物)对冠心病-不稳定型心绞痛(UA)合并抑郁症状患者治疗的疗效。方法:将62例不稳定型心绞痛合并抑郁症状的患者随机分为观察组和对照组。观察组在常规药物治疗基础上给予路优泰300mg,日3次口服;对照组给予单纯常规药物治疗。于治疗后4周观察两组间心前区疼痛和心电图的变化情况,并采用SDS、HAMD抑郁量表进行动态评估。结果:观察组4周内抑郁情绪及心前区疼痛症状明显改善,与对照组比较有显著性差异(P<0.05)。结论:路优泰能有效的减轻冠心病患者的抑郁情绪,改善不稳定型心绞痛患者心前区疼痛症状,这种治疗更有利于冠心病的控制。
Objective ： To observe antidepressants Neurostan （ St. · John Wort extract ） on coronary heart disease-unstable angina （UA）patients with depressive symptoms combined effect. Method ： 62 patients with unstable angina pain combined depression were randomly divided into two groups. Study group on the basis of conventional drug treatment given Neurostan 300rag, rid, po; control group received routine treatment alone. 4 weeks after the treatment were observed between chest pain and ECG changes, and using SDS, HAMD depression scale for dynamic assessment. Results ： Group 4 weeks, depression and chest pain symptoms improved, compared with the control group there was significant difference （ P〈0.05 ） .Conclusion ： Neurostan can effectively relieve depression in patients with coronary heart disease, Improvement in patients with unstable angina chest pain symptoms, this treatment is more conducive to coronary heart disease control.
出处
《辽宁中医药大学学报》
CAS
2011年第7期194-195,共2页
Journal of Liaoning University of Traditional Chinese Medicine
