摘要
介绍近几年已报道的有关受体介导的肝靶向载药系统的研究情况。近年来受体介导的肝靶向载药系统的研究取得了一些可喜进展,相关配体-受体可与药物、脂质体、纳米粒、基因、偶联物等相连,提高药物或载体的肝靶向能力。受体介导机制在肝靶向载药系统的研究领域具有广阔的应用前景,尤其是肝脏特异性受体的不断发掘,丰富了肝主动靶向的理论体系,展示了肝脏疾病治疗的美好未来。
This paper summarizes the studies on receptor-mediated liver targeting drug-loading system in recent yeas.The research on receptor-mediated liver targeting drug-loading system has made some encouraging progress.The ability of liver targeting can be improved by the ligand-receptor connecting with drugs,liposomes,nanoparticles,gene,conjugate,etc.The application of the receptor-mediated mechanism has wide application prospects in the field of liver targeting drug-loading system.Especially the development of the specific liver receptors enrichs the theoretical system of active transport pathways and shows the bright future in the treatment of liver diseases.
出处
《中国药业》
CAS
2011年第12期17-19,共3页
China Pharmaceuticals
关键词
肝靶向
受体
载药系统
liver targeting
receptor
drug-loading system
