摘要
目的：探讨选择性动脉化疗药物灌注及栓塞治疗结直肠癌肝转移的价值。材料与方法：对27例失去手术机会的结直肠癌肝转移患者，采用经股动脉穿刺，选择性肝动脉插管灌注化疗药物（ADM，CBP，FUDR），并用ADM及碘化油乳化后栓塞肝动脉。结果：在第1疗程结束后，19例患者肝内肿瘤有缩小，25例CEA降低，23例上腹疼痛减轻或消失。1、2、3年生存率分别是70.4％、51．9％、22.2％。结论：经肝动脉化疗药物灌注及栓塞治疗是失去手术机会的结直肠癌肝转移患者的一种安全、有效的姑息性治疗方法。
Objective: To evaluate the selective hepatic arterial infusion chemotherapy and embolization (HAICE) in treating of unresectable li-ver metastases from colorectal cancer. Materials and Methods: Percutaneous selective hepatic arterial infusion chemotherapy (Adriamycin, Carbo-platin, 5-fluorouracil) and embolization (mixture of iodic oil and ADM) was Performed in 27 patients with unresectable colorectial liver metastases.Results:After the first therapeutic course was given, the liver lesions regressed in size in 19 cases, and CEA level was decreased in 25 cases. Thesurvival rates at 1, 2, and 3 year were 70. 4%, 51. 9% and 22. 2%, respectively. Conclusion: HAICE is a safe and effective palliative treatmentfor patients with unresectable colorectal liver metastases.
出处
《临床放射学杂志》
CSCD
北大核心
1999年第12期762-764,共3页
Journal of Clinical Radiology
关键词
结肠癌
直肠癌
药物序法
动脉栓塞
肝转移瘤
Colorectal cancer Infusion chemotherapy Arterial embolization Liver metastases
