摘要
目的:观察棘白菌素类抗真菌药物卡泊芬净治疗重症患者的侵袭性真菌感染(IFI)的疗效。方法:回顾性分析2008年1月～2010年8月我科接受卡泊芬净治疗的32例重症患者。32例患者中确诊IFI 10例(白色念珠菌感染6例,热带念珠菌感染3例,近平滑念珠菌1例);临床诊断IFI 12例(白色念珠菌7例,热带念珠菌2例,光滑念珠菌2例,曲霉菌1例);疑似IFI 10例,病原菌不确定。结果:32例患者中,痊愈9例,显效14例,进步5例,无效4例,死亡3例。结论:卡泊芬净是治疗危重患者侵袭性真菌感染有效且相对安全的药物。
Objective： To explore the efficacy of caspofungin in the invasive fungal infection（IFI） in intensive care unit.Methods： From January 2008 to August 2010,32 patients of IFI were treated by caspofungin.10 cases were proven（6 albicans,3 tropicalis,1 parapsilosis）.12 cases were probable（7 albicans,2 tropicalis,2 glabrata,1 aspergillus species） and 10 cases were possible.Results： 9 cases were cured,14 cases were markedly improved,5 cases were improved and 4 cases were failed,3 cases were died.Conclusion： Caspofungin is effective and safe in the treatment of invasive fungal infection of intensive care unit.
出处
《中国医药导报》
CAS
2011年第18期55-56,共2页
China Medical Herald
关键词
真菌感染
重症患者
卡泊芬净
Invasive fungal infection
Intension care unit
Caspofungin
