摘要
慢性乙型肝炎病毒(HBV)感染免疫耐受期与HBV感染非活动状态患者,肝脏炎症活动度为G0者,仅占10%-20%,肝小叶及汇管区均未见或仅有少许炎细胞浸润,汇管区与肝实质交界处无炎症表现,汇管区无明显扩大,无明显纤维组织增生。肝星形细胞(HSCs)、树突状细胞(DCs)、库普弗细胞(KCs)和肝窦内皮细胞(LSECs)等肝非实质细胞,不但参与人体对病毒感染的抵抗和防御,还在HBV慢性感染免疫耐受期起着重要作用。
Immune tolerance of HBV infection and in patients with non-active state whose inflammation activity of hepatic as G0 grade those only about 10% to 20%.Hepatic lobule and portal tracts are no or only little inflammatory cell infiltration,portal tracts at the junction with no inflammation,no significant increase in portal area,no obvious fibrous tissue hyperplasia.HSCs,DCs,KCs and LSECs and other liver non-parenchymal cells,not only in the body's resistance to viral infection and defense,also of HBV chronic infection plays an important role in immune tolerance.
出处
《中国医药导报》
CAS
2011年第18期10-12,共3页
China Medical Herald
基金
首都医科大学基础临床合作基金(编号:09jl56)
关键词
HBV慢性感染
免疫耐受
肝组织病理
Chronic hepatitis B virus infection
Immune tolerance
Hepatic pathology