摘要
原发性肝癌是最常见的恶性肿瘤之一.由于其死亡率高,现已有很多研究为其临床的治疗提供基础依据.在这些研究中,肝癌动物模型的使用很广泛.以下我们回顾现今常用的肝癌动物模型,并对未来肝癌动物模型的发展做一重点介绍.
Primary liver cancer remains one of the most lethal malignancies worldwide. As this disease is lethal in most cases, research has to be done to improve our understanding of the disease and to offer insights for possible treatment options. Animal models have been widely used in the research of primary liver cancer. Here, we review the progress and prospects for the development of animal models of primary liver cancer, highlighting the best candidates for future preclinical investigations.
出处
《世界华人消化杂志》
CAS
北大核心
2011年第12期1275-1278,共4页
World Chinese Journal of Digestology
关键词
原发性肝癌
小鼠模型
基因工程小鼠
Primary liver cancer
Mouse model
Genetically engineered mice
