摘要
目的回顾45例急性重症心肌炎(AVM)患者接受体外膜肺氧合(ECMO)治疗的经验,探索左心室射血分数(LVEF)对此类患者预后的影响。方法回顾性分析2006年1月～2011年3月45例AVM患者接受ECMO治疗的情况。ECMO治疗期间每天通过心脏彩超计算LVEF,并计算出治疗期间的平均LVEF。平均LVEF≥0.27的患者纳入第一组,其余患者纳入第二组。对比两组患者的病死率及并发症发生率。结果 ECMO支持平均时间为(38±20)h,36例脱机,32例出院。第一组包括26例,平均LVEF为(0.32±0.2),第二组包括19例,左心室平均射血分数为(0.23±0.3)。两组左心室平均射血分数及院内病死率差异有统计学意义(P<0.05),而两组ECMO相关并发症发生率差异无统计学意义(P>0.05)。结论 LVEF水平与AVM患者行ECMO治疗的病死率存在负相关关系,提示LVEF可能是预测此类患者预后的指标之一。
Objective In this study,we reviewed our experiences with extracorporeal membrane oxygenation support and tried to identify the relationship between left ventricular ejection fraction and clinical outcomes.Methods We retrospectively analyzed clinical records of 45 consecutive patients, from January 2006 to March 2011,receiving ECMO support.Left ventricular ejection fraction levels were monitored and recorded every day during the support period.The mean left ventricular ejection fraction level was calculated for all patients for whom result data were available.Patients with mean left ventricular ejection fraction≥0.27 were allocated to groupⅠ.The others were allocated to groupⅡ.Clinical outcomes were compared with groups.Results Twenty six patients were allocated to group Ⅰ with mean left ventricular ejection fraction of （0.32±0.2）.The other 19 patients allocated to group Ⅱ with mean left ventricular ejection fraction of（0.23±0.3）.There is significant difference in the mortality of the two groups（P0.05）.But perioperative complications were similar between the two groups.Conclusion The level of left ventricular ejection fraction may be associated with mortality in patients receiveing extracorporeal membrane oxygenation.
出处
《中外医学研究》
2011年第17期14-15,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
