摘要
目的研究胃癌患者舌苔特点及与表皮生长因子(EGF)之间的关系。方法以71例胃癌患者为研究对象,并以40例正常人作为对照,酶联免疫分析(ELISA)法检测血清中EGF水平,观察记录舌象,将舌苔分为薄白、薄黄等6种舌苔类型进行分析。结果胃癌患者舌苔以腻苔为多,其次是剥苔;胃癌组血清EGF水平明显高于正常组(P<0.01),不同类型舌苔的血清EGF含量均高于正常组,包括正常组舌苔在内的7组舌苔之间经统计分析有明显的差异(P<0.01)。结论胃癌患者舌苔变化明显,且血清EGF与舌苔变化有一定的关系。
OBJECTIVE To study the characteristics of gastric cancer patients＇ tongue coating and its relationship with epidermal growth factor（EGF）.METHODS 71 patients with gastric cancer were considered as study subjects and 40 normal people were selected as control.Based on human EGF enzyme-linked immunosorbent assay（ELISA）,EGF in serum was detected,tongue appearance were observed and recorded.The tongue coating was divided into six types,such as thin whitish coating,thin yellowish coating and so on to analyze.RESULTS Patients with gastric cancer frequently manifested greasy tongue coating,secondly being peeled coating;serum EGF in gastric cancer group was conspicuously higher than in the normal group（P0.01）,serum EGF contents of different types of tongue coating were all higher than those of the normal group and there were significant differences among seven groups of tongue coating including the normal group according to statistical analysis（P0.01）.CONCLUSION Patients with gastric cancer have distinct tongue coating variations and there is certain correlation between serum EGF and tongue coating variations.
出处
《南京中医药大学学报》
CAS
CSCD
北大核心
2011年第3期220-222,共3页
Journal of Nanjing University of Traditional Chinese Medicine
基金
国家自然科学基金(30973715)
江苏省自然科学基金(BK2008461)
关键词
胃癌
舌苔
EGF
gastric cancer
tongue coating
EGF
