摘要
目的 探讨代谢综合征患病率随性别和年龄的变化趋势。方法对2006年1～12月和2009年1～12月笔者医院的健康体检人群进行回顾性调查。男性：2006年1619例，2009年2202例；女性：2006年418例，2009年636例。MS诊断标准采用NCEP—ATPⅢ的中国人修订标准。结果男性2009年的MS患病率（41．2％VS 36．6％，P=0．003）较2006年显著增加了4．6％；女性2009年MS患病率（33．2％VS 36．1％，P〉0．05）较2006年降低了2．9％。年龄分层显示，男性在44岁以下MS患病率有下降趋势，45岁后各年龄组皆呈增加趋势，特别是45～64岁年龄段MS患病率显著增加（P〈0．05）；女性年龄小于64岁MS患病率呈降低趋势，65岁后呈增加趋势。2006-2009年MS各危险因子变化率比较显示，2009年男性WC、HDL-C、FPG阳性例数明显增加（P〈0．05）；女性TG阳性例数明显减少（P〈0．05）。结论2006-2009年北京某公司MS患病率变化趋势呈现明显的性别和年龄差异。男性45～64岁和女性65岁后人群是MS患病的重点防治人群。
To investigate the age and gender specific trends of prevalence of metabolic syndrome （MS）. Methods A retrospective cross - sectional study was performed from 2006 to 2009. 1619 men and 418 women in 2006, 2202 men and 636 women in 2009, respectively, were recruited from our hospital. MS was defined according to the National Cholesterol Education Program -Adult Treatment Panel Ⅲ（ NCEP - ATPⅢ ） criteria modified for Chinese subjects. Results Compared with subjects in 2006, the trend of prev- alence of MS （41.2% vs 36.6%, P=0.003） increased 4.6% in men, and decreased 2.9% in women （33.2% vs 36. 1%, P〉 0.05） , respectively. They were stratified by age of interval 10 years old as a subgroup. In men, the trend of prevalence of MS decreased in subjects below 44 years old, and increased in subjects above 45 years old, especially significantly increased in subjects in the intervals of 45 - 64 years old （P 〈 0.05）. In women, the trend of prevalence of MS decreased in subjects below 64 years old, and increased in subjects above 65 years old. As we comparing the changes of incidence of components of MS in subjects between 2006 and 2009, the trend of prevalence increasing were seen for elevated waist circumference, fasting blood glucose and lowed high - density lipoprotein cholesterol in men, and decreasing for triglyceride in women, respectively. Conclusion The age and gender trends of prevalence of MS in 2006 were significantly different from 2009 in employees of one company in Beijing. The subjects aged 45 - 64 in men and 65 in women were the em- phasis on the prevention of MS.
出处
《医学研究杂志》
2011年第5期88-91,共4页
Journal of Medical Research
