摘要
目的比较乳腺管状腺癌(tubular carcinoma,TC)与浸润性导管癌(invasive ductal carcinoma,IDC)的临床病理特征和预后。方法回顾性分析1996—2009年乳腺癌手术治疗分期为I/II的41例TC患者和分期为I/II的2 568例IDC患者的临床资料,比较两者的临床病理特征和预后。结果与IDC相比较,TC更容易用钼靶X线检测出(71%vs.22.9%,P<0.05),肿物较小,很少有淋巴结浸润(8.6%vs.22.9%,P<0.05)。TC和IDC的复发率分别为7.9%和25.7%(P<0.05),TC的无病生存期显著高于IDC(P<0.05)。结论 TC有着较好的临床病理特征和预后。此外,TC患者与正常人的预期寿命相似,所以辅助性化疗可能不适于作为TC的常规治疗。
Objective To compare the clinicopathologic features and prognosis between tubular carcinoma（TC） and invasive ductal carcinoma（IDC） of the breast.Methods The clinical data of 41 patients with stage I/II TC and 2 568 patients with stage I/II IDC,treated with breast surgery,from 1996 to 2009,were analyzed retrospectively,and the clinicopathologic features and prognosis between the 2 groups were compared.Results Compared with IDC,TC was more likely to be detected by mammographic screening（71% vs.22.9%,P0.05）,and had smaller median size and showed less lymph invasion（8.6% vs.22.9%,P0.05）.The rate of recurrence in TC and IDC was 7.9% and 25.7%（P0.05）,respectively.The disease-free survival of TC was higher than IDC（P0.05）.Conclusions TC is associated with more favorable clinicopathologic features and outcome.In addition,the life expectancy of patients with TC is similar to that of normal individuals,and as a consequence,adjuvant systemic chemotherapy may not be justified as routine management for TC.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2011年第5期467-470,共4页
China Journal of General Surgery
关键词
乳腺肿瘤/病理学
管状腺癌
导管癌
预后
Breast Neoplasms
Tubular Carcinoma
Ductal Carcinoma
Prognosis
