摘要
输血相关性急性肺损伤（transfusion-related acute lung injury,TRALI）是一种与输入含血浆血制品相关的可危及生命的临床综合征，虽然很多资料认为TRALI通常发生在输血后6小时内，但一些来自危重患者的资料显示存在一种称为“迟发性TRALI”的情况，即发生在输血6小时后的TRALI。迟发性TRAM综合征常发生在输血后6～72小时，多达25％的接受输血的危重患者发生迟发性TRAH，病死率高达40％。本文对迟发性TRAH从诊断、治疗及预防几个方面做简单的讨论，该综合征的临床判断及实验室检查水平仍有待提高。
Transfusion -related acute lung injury （TRALI）is a life -threatening clinical syndrome associated with the transfusion of plasma - containing blood components. Although most sources agree that TRALI usually occurs within 6 h of transfusion, some new informations from critically ill patients has suggested that a condition called flelayed TRALImay exist, which develops more than 6 hours after the transfusion. Delayed TRALI syndrome often develops 6 -72 hours after the transfusion, occurring in up to 25% of critically ill patients receiving a blood transfusion, and is associated with a mortality of up to 40%. We discuss the diagnosis, treatment and prevention of delayed TRALI, the level of clinical diagnosis of the syndrome and the laboratory test still need to be improved.
出处
《中国急救医学》
CAS
CSCD
北大核心
2011年第5期468-472,共5页
Chinese Journal of Critical Care Medicine
关键词
迟发性输血相关性急性肺损伤
输血相关性急性肺损伤
诊断
治疗
预防
Delayed transfusion - related acute lung injury （TRALI）
Transfusion - related acute lung injury （TRALI）
Diagnosis
Treatment
Prevention
