摘要
目的探讨生殖道B族溶血性链球菌(GBS)感染与稽留流产的关系。方法对86例稽留流产病人,67例孕早中期正常妊娠引产病人阴道分泌物、宫腔内吸出物、羊水做GBS培养,同时检测宫颈支原体、沙眼衣原体以排除其他可能致病因素。结果研究组和对照组阴道分泌物GBS培养阳性率分别为16.28%(14/86)和11.94%(8/67),差异无显著性(P=0.672);研究组和对照组宫腔内吸出物(或羊水)GBS培养阳性率分别为1.16%(1/86)和0%例;研究组GBS合并支原体感染5例,占5.81%,合并衣原体感染3例,占3.49%;对照组GBS合并支原体感染4例,占5.97%,衣原体感染1例,占1.49%,P值分别为0.734、0.575,差异无显著性。但研究组支原体阳性44例,占51.16%,而对照组阳性20例,占29.85%,差异有显著性。结论部分妊娠妇女生殖道可携带GBS,但与早期流产无正相关,如无诱因在妊娠早中期尚不能直接侵入羊膜腔引起宫内感染,无需过早干预。但支原体感染可能与胚胎停止发育有关,是导致胚胎停止发育的原因之一。
Objective To explore the relationship between the colonization of group B streptococci（GBS） infection and missed abortion.Methods Totally 86 patients（study group） who experienced the missed abortion during their first or second trimester and 67 women in control group.The vaginal secretions,intrauterine aspirate and amniotic fluid were collected for the GBS culture,Cervical Mycoplasma（UU＋MH） and chlamydi trachomatis（CT） were detected at the same time.Results Positive results of GBS culture of vaginal secretions were detected in 14 patiens（16.28%） in the Study Group,but only 8 patients（11.94%） in control group（P=0.672）.Positive results of GBS culture of the intrauterine aspirate samples were detected in 1 patients（1.16%）,but there were all negative in control group.The rate of concurrent infection of GBS and mycoplasma was 5.81%（5/86） in the study group and 5.97%（4/67） in the control group（P=0.734）.The rate of concurrent infection of GBS and CT were 3.49%（3/86）and 1.49%（1/67） in the control group（P=0.575）.The positive rates of UU and MH were 32.56%（28/86）and 20.89%（14/86）in the study group,but were only 18.60%（16/67）（P=0.023） and 8.96%（6/67）（P=0.0104） in the control group.Conclusions Part of pregnant women carries GBS in genital tract,however,that is no positive correlation with early abortion.If there is no predisposing cause,the GBS can not directly invade the amniotic cavity or cause the intrauterine infection in the first or second trimester of pregnancy.That is to say,there is no need to early intervene.Yet the mycoplasma infection may be one of the reasons leading to arrested intrauterine pregnancy.
出处
《齐齐哈尔医学院学报》
2011年第6期874-875,共2页
Journal of Qiqihar Medical University
基金
深圳宝安区科技立项(编号:2009379)
关键词
B族链球菌
感染
稽留流产
支原体
衣原体
Group B streptococci Infection Missed abortion Mycoplasma Chlamydia
