摘要
目的观察参麦注射液联合CAG方案治疗老年急性髓系白血病(AML)的临床疗效及不良反应。方法 42例初治老年AML患者随机分为两组。联合治疗组(20例)以参麦注射液联合CAG方案治疗;对照组(22例)则仅采用CAG方案治疗。结果两组治疗总有效率分别为65.0%和59.1%,差异无统计学意义(P>0.05);两组患者治疗后红细胞、白细胞、血红蛋白和血小板等均明显下降(P<0.05),而对照组治疗后下降更为明显(P<0.05);两组不良反应发生率分别为45.0%和63.6%,两组比较差异有统计学意义(P<0.05)。结论参麦注射液联合CAG方案治疗老年急性髓系白血病具有缓解骨髓抑制,减轻不良反应的作用,值得在临床推广。
Objective To observe the clinical effect and side effects of Shenmai injection combined with CAG regimen in treatment of elderly acute myeloid leukemia.Methods Forty-two cases of elderly patients with AML were randomly divided into two groups.Combined treatment group（twenty cases） were treated with Shenmai Injection combined with CAG regiment;control group（twenty-two cases） were only treated with CAG regiment.Results The total effective rates were 65.0% and 59.1% respectively,there was no significant difference between two groups（P0.05）;The levels of red blood cells,white blood cells,hemoglobin and platelet in two groups decreased significantly（P0.05）,while the control group decreased more than combined treatment group（P0.05）;the adverse events of two groups were 45.0% and 63.6%,there was a significant difference between the two groups（P0.05）.Conclusions Shenmai Injection combined with CAG regimen on treatment of elderly acute myeloid leukemia can remit marrow suppression and reduce side effects,it would be valuable to widespread popularization.
出处
《中国误诊学杂志》
CAS
2011年第16期3800-3801,共2页
Chinese Journal of Misdiagnostics
