摘要
根据世界卫生组织的定义,药物警戒是"发现、评价、理解和预防不良反应或其他任何可能与药物有关问题的科学研究与活动[1]"。药物警戒系统作为一种安全工具在公众药物使用和公众健康有关方面发挥着十分重要的作用。对大多数发展中国家而言,公共领域内的药物安全问题不仅是政府的职责,而且是衡量社会进步的重要指标。因此,建立起一个良好的药物警戒系统不仅是社会发展过程中的必然追求,同时也是一个挑战。发展中国家(如阿尔及利亚)现存的问题是,如何将重心从正在进行的基础性工作(如药物不良反应监测)转移到构建出一个完善的药物警戒系统上来。药物警戒的工作内容主要包括:培训执业医师使用最有效的药物达到更安全的目的;根据不同患者的病理状态,选择适当的给药剂量和给药间隔进行治疗;观察治疗的花费以保证其维持在个人和社会都可承受的范围内。
According to the definition of WHO,Pharmacovigilance is ＂the science and activity of testing,evaluating,understanding and preventing ADR（adverse drug reactions）and other relevant drug problems＂.The Pharmacovigilance System acts as an important safety tool in regards to both public drug use and public health.To most developing countries,drug safety within the public realm is not only the duty of the government but also an important indicator of social progress.Therefore,it is not only a requisite for the social development process but also a challenge to establish a satisfactory Pharmacovigilance System.The problem presented to developing countries such as Algeria is how to shift from ongoing fundamental work such as monitoring the ADR,to constructing an ideal Pharmacovigilance System.A preventive Pharmacovigilance is achieved when it starts to train medical practitioners to use the most effective drugs to better safety,tailored to each patient,administered at the right dose and for an adequate duration according to the pathology to treat,and watch in addition the cost of treatment to maintain it affordable for the individual and the community.
出处
《北方药学》
2011年第3期68-71,共4页
Journal of North Pharmacy
关键词
药物警戒
发展中国家
Pharmacovigilance
developing countries
