摘要
应用膜片钳技术对晶体细胞的研究始于９０ 年代初。结果表明，晶体细胞膜上存在着不同类型的离子通道，它们对于调节细胞水合状态具有重要意义，从而影响晶体透明性。在晶体电生理特性研究中，多种模式的膜片钳技术得到了广泛应用。不仅记录了晶体细胞膜上多种通道活动，还测量了不同种属晶体上皮细胞的静息膜电位和膜电容，以及位于晶体内不同深度的晶体纤维细胞间的缝隙连接电阻。
The study of lens cells by patch clamp technique began in the early 90's. It shows that the membrane of lens cells possess different types of ionic channels. These channels are responsible for the modulation of the hydration state and transparency of lens. Several patch clamp configurations have been used to study the activity of ionic channels .The resting potential and capacitance as well as resistance of different lens cells were also measured.
出处
《航天医学与医学工程》
CAS
CSCD
1999年第6期456-458,共3页
Space Medicine & Medical Engineering
关键词
膜片钳技术
离子电流
视觉障碍
晶状体
patch clamp technique
ion currents
vision disorders
crystalline lens
