摘要
目的应用超声评价类风湿关节炎(RA)患者颈总动脉,厚度(TMT)和血清动力学变化.方法根据纳入标准分为RA血脂水平升高组(RA1组)16例、RA血脂水平正常组(RA2组)23例及正常对照组20例,应用高频超声测量双侧颈动脉内-中膜厚度(IMT)、颈总动脉内径(Dn)、收缩期峰值流速(PSV)、舒张末期流速(EDV)及阻力指数(R)I,并进行对比分析.结果 (1)RA1组、RA2组患者颈动脉IMT较正常对照组增厚(P<0.05);RA1组较RA2组患者颈动脉IMT增厚(P<0.05);(2)RA1组、RA2组患者颈动脉Dn较正常对照组增宽(P<0.05);(3)RA1组、RA2组及正常对照组PSV、EDV及RI值无明显差异(P>0.05).结论 RA患者IMT增厚、Dd增宽,高血脂类风湿关节类动粥样硬化IMT血流程度高于血脂患者,并与其血脂水平相关.超声可作为早期预测RA患者动脉粥样硬化有效的、简便且无创的手段.
Objective Combining with patients＇s lipid levels,to evaluate carotid artery atherosclerosis（CAS）in patients with rheumatioid arthritis by ultrasonography.Methods The carotidarteries were assessed by ultrasonography in 16 RA patients with high lipid levels（RA1 group）,23 RA patients with nomal lipid levels（RA2 group）and 20 healthy volunteers（normal control group）.IMT,Dd,PSV,EDV and RI of common carotid arteries were measured by ultrasonography in the three groups.Results IMT of RA1 and RA2 patients were thicker than that of healthy volunteers.IMT of RA1 groups were thicker than RA2 groups.Dd was higher in RA patients than that of healthy volunteers.There was no significant difference in PSV,EDV,and RI among the three groups（P0.05）.Conclusions Eaerly sign of carotid atherosclerosis（increased IMT and Dd）is more frequently detected in RA,and it was correlated with lipid levels.Arteriosclerotic examine technique by ultrasonograph can provide an early,simple,noninvasive way for vasculopathy testing.
出处
《昆明医学院学报》
2011年第3期56-58,62,共4页
Journal of Kunming Medical College
