过氧化物酶增殖物激活受体γ与固醇调节元件结合蛋白-1c的研究进展
摘要
非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD),从病理上分为单纯性脂肪肝、脂肪性肝炎、脂肪性肝纤维化和脂肪性肝硬化.国内外研究发现众多肥胖相关因子都与之相关,过氧化物酶体增殖物激活受体γ(Proliferator-Activated Receptorγ,PPAR-γ)与固醇调节元件结合蛋白-1c (sterol regulatory element-binding protein-1,SREBP-1c)就是其中的两个重要的相关因子[1].
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