摘要
目的探讨2型糖尿病患者(T2DM)中C-反应蛋白(CRP)和糖化血红蛋白(HbA1C)与糖尿病视网膜病变(DR)的关系。方法随即分组,检测20例正常对照组、20例糖尿病无视网膜病变(NDR)、20例非增生性糖尿病视网膜病变(NPDR)和20增生性糖尿病视网膜病变(PDR)患者中血清中CRP和HbA1C含量,并分析各组变化。结果 T2DM患者CRP和HbA1C随着DR的病变程度逐步增加,差异有显著性(P<0.05),两者之间成正相关。结论 CRP和HbA1C是DR发生、发展的危险因素,并能预测DR的风险和严重程度。
Objective To clarify the relationship between CRP,HbA1C and diabetic retinopathy in type 2 diabetes mellitus.Methods Random grouping,we dectected HbA1C and CRP levels in patients serum from 20 cases of normal control group,20 patients with diabetes without retinopathy（NDR）,20 cases of non-proliferative diabetic retinopathy（NPDR） and 20 proliferative diabetic retinopathy（PDR）.we analyzed the change in each group.Results T2DM patients with CRP and HbA1C level gradually increased with DR stage,the difference was significant（P0.05）,the two was a positive correlation.Conclusions The level of CRP and HbA1C was occurrence and development of risk factors to DR and could predict the occurrence risk of DR in type 2 diabetic patients
出处
《临床眼科杂志》
2011年第2期130-132,共3页
Journal of Clinical Ophthalmology
