摘要
目的:探讨应用彩色多普勒方法制备臂丛神经损伤模型的可行性并对断端及缺损长度进行观察。方法:健康成年新西兰大耳白兔10只,设动物两侧自身对照,分为两组,各组10侧。均应用SonoScape S8便携式彩超仪,探头频率9～13 MHz,观察活体臂丛神经,并记录解剖定位特征。左侧制作臂丛神经损伤开放性损伤模型,右侧在超声引导下制作臂丛神经损伤闭合性损伤模型,观察造模前后超声影像学变化及组织病理学形态改变。结果:高频超声能够显示小于1 mm兔臂丛神经,并依据彩色多普勒血流分布显示与之相伴行的血管关系,观察臂丛神经损伤后的断端及周围软组织改变,对臂丛神经损伤进行定位。结论:在超声引导下可制备兔臂丛神经闭合性损伤模型,为臂丛神经损伤的诊断和超声影像学评估的准确定位,提供良好的动物模型实验基础。
Objective：To explore the feasibility of preparing the model of the brachial plexus by the method of color Doppler ultrasound and observe the fracture level and the defect length.Methods： Ten healthy adult New Zealand rabbits were divided into two groups,10 in each group with self double side control.Then portable SonoScape color Doppler instrument with the probe coil of 9 to13 MHZ frequency was used in each side to observe the living brachial plexus and record the feature of the anatomical localization.On the left side,the model of open injury of the brachial plexus was produced while on the counterpart of the right arm,the model of the brachial plexus injury was made under the guidance of the ultrasound,and then the changes of the ultrasound imaging and tissue＇s pathology patterns were observed before and after the modeling.Results：The rabbit brachial plexus of less than 1mm length and the concomitant vascular relationship on the basis of the blood flow distribution on the color Doppler can be displayed by ultrasound.The changes of the vaginal cuff and the surrounding tissues after the brachial plexus＇ injury can be observed and the brachial plexus injury can be finally located.Conclusion：Under the guidance of the ultrasound,a model of injury of the brachial plexus can be established,which may provide a good experimental basis of animal model for the clinical diagnosis of the brachial plexus injury and accurate location.
出处
《西北国防医学杂志》
CAS
2011年第2期109-111,共3页
Medical Journal of National Defending Forces in Northwest China
