摘要
目的检测食管癌患者血清胰岛素样生长因子-1(IGF-1)及癌胚抗原(CEA)的浓度并探讨其临床意义。方法应用化学发光法检测54例食管癌患者和22例正常人的血清IGF-1及CEA的浓度。结果正常健康人血清IGF-1的含量为(196.75±58.31)ng/ml,血清CEA值为(5.4±1.9)ng/ml,而食管癌患者血清IGF-1含量为(1092.59±311.44)ng/m l,血清CEA值为CEA为(30.2±14.1)ng/ml。食管癌患者组明显高于正常对照组(P<0.01),且血清IGF-1水平及CEA值随临床病理分期的进展而逐步增高(P<0.05)。结论血清中高水平的IGF-1和CEA可能成为食管癌的一个报警信号,在一定程度上反映食管癌的病情进展,有利于治疗措施的选择和预后的判断。
Objective To detection the serum insulin-like growth factor-1（IGF-1）level and carcinoembryonic antigen（CEA） in patients with esophageal cancer and investigate its clinical significance.Methods The serum IGF-1 level and CEA is determined by chemiluminescence assay in 55 esophageal cancer patients,22 normal subjects are taken as control group.Results The IGF-1 level of nomal control group is（196.75±58.31）ng/ml,The CEA level of nomal control group is（5.4±1.9） ng/ml.the IGF-1 and CEA of patients are（1092.59±311.44）ng/ml and 30.2±14.1 ng/ml,which are higher than that of the control（P〈0.01）.The level of IGF-1 and CEA also elevate as the clinical pathological tumor stages（P〈0.05）.Conclusions The hight level of serum IGF-1 and CEA will be a warning signal of esophageal cancer.They can profit the choice of the therapeutic measure and judgement of the prognosis.
出处
《医药论坛杂志》
2011年第6期54-56,共3页
Journal of Medical Forum
