摘要
目的了解江苏高邮农村代谢综合征(MS)患病分布情况。方法 2009-12-2010-05,对江苏高邮农村18~74岁汉族居民进行抽样调查,包括标准化的问卷调查,测量血压、腰围、臀围及体质量指数、腰臀比等体格指标并采血进行血糖、血脂等生化指标检验,共对4493份资料进行分析。对入选居民分别根据国际糖尿病联盟(IDF)推荐的有关中国人MS的诊断标准和美国胆固醇教育计划成人教育组Ⅲ(NCEP-ATPⅢ)亚洲人群修订标准诊断MS,计算MS患病率,采用多变量logistic回归分析MS患病率相关因素。结果江苏高邮农村18~74岁汉族居民,MS患病粗率:IDF标准为27.0%(男性为20.5%,女性为32.7%,P<0.01),NCEP-ATPⅢ标准为16.2%(男性为15.6%,女性为16.8%,P=0.296);根据中国人口年龄进行标化后,MS患病率:IDF标准为16.3%(男性为16.0%,女性为18.0%);NCEP-ATPⅢ标准为9.4%(男性为11.0%,女性为9.1%)。两种诊断标准有较好的符合率(87.7%)。45岁以前,MS患病率随年龄增加而升高,男性高于女性,差异有统计学意义(P<0.01);45岁以后,MS患病率女性随年龄增加而升高,而男性随年龄增加而降低,女性高于男性,差异有统计学意义(P<0.01)。Logistic回归分析提示MS患病率与性别、糖尿病家族史、高血压家族史、教育程度、体力活动、脉压、静息心率、糖化血红蛋白、血尿酸等因素相关。结论江苏高邮农村18~74岁汉族居民MS患病率略高于国内其他地区。应采取综合措施降低MS发生率。IDF标准和NCEP-ATPⅢ诊断符合率较好,但IDF标准更适用于中国人群。
TitlePrevalence and risk factors of metabolic syndrome among 18 to 74 years old rural population of Gaoyou in Jiangsu AuthorXU Fang,ZHANG Hai-feng,ZHU Zhen-yan,YAO Wen-ming,LI Jing,GUO Jing,ZHOU Yan-li,YANG Tao,GONG Lei,CAO Ke-jiang,LI Xin-li Department of Cardiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China Objective To investigate the prevalence and risk factors of metabolic syndrome(MS)among 18 to 74 years rural population of Gaoyou.Methods A total of 6000 individuals were surveyed by stratified-cluster random sampling,4493 data analyzed.An questionnaire survey,physical examination and laboratory tests were conducted among all the people.Prevalence of MS was calculated respectively according to both the criterions of IDF and NCEP-ATPⅢ.The risk factors were analysised.Results The crude prevalence of MS was 27.0%(men 20.5%,women 32.7%,P〈0.01)according to the diagnostic criteria of IDF,while 16.2%(men 15.6%,women 16.8%,P=0.296)according to NCEP-ATPⅢ(2005).Standardized rate of MS was 16.3%(men 16.0%,women 18.0%)according to IDF and 9.4%(men 11.0%,women 9.1%)according to NCEP-ATPⅢ.The agreement rate of these two MS diagnostic criteria was 87.7%.In people younger than 45,the prevalence of MS increased with age and was higher in men than in women(P〈0.01),while in people older than 45,the prevalence of MS increased in woman but decreased with age in men,and was higher in women than in men(P〈0.01).Gender,family history of diabetes mellitus,family history of hypertension,education,physical activity,pulse pressure,resting heart rate,glycosylated hemoglobin and blood uric acid were related to the prevalence of MS.Conclusion Theprevalence of the MS among 18 to 74 years rural population of Gaoyou was higher than the nation-wide average.The MS diagnostic criteria of IDF and NCEP-ATPⅢ are in good accordance.Comprehensive measures of interventions should be strongly advocated among adults. KeywordsMetabolic syndrome;Prevalence;Risk factors;Epi
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2011年第4期329-335,共7页
Chinese Journal of Hypertension
基金
"十一五"国家科技支撑计划"全科型乡镇卫生院技术集成综合示范"(2008BAI65B09)
"十一五"国家科技支撑计划"慢性阻塞性肺炎等疾病防治技术研究"(2007BAI07A10)
"江苏省亚健康高危人群综合干预示范研究"(BE2009613)