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替米沙坦对轻中度高血压患者QT离散度的影响

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摘要 目的探讨替米沙坦对轻中度高血压患者QT离散度(QTd)的影响。方法 60例轻中度高血压首诊患者给予替米沙坦80mg/d治疗,必要时加用双氢氯噻嗪12.5mg/d,总疗程24周。分别于治疗前、后测量血压、左室重量指数(LVMI)、QT间期及QTd。结果替米沙坦治疗后,患者血压从(168.81±15.01/)(108.54±7.35)mmHg降至(136.47±10.24)/(89.57±5.96)mmHg,QTcd由(52.39±24.71)ms降至(42.62±25.37)ms,LVMI由(151.63±35.45)g/m2降至(137.82±29.16)g/m2,差异均有统计学意义(均<0.05)。QTcd与LVMI呈正相关(0.412,<0.01)。结论替米沙坦能降低轻中度高血压患者的QTd,可能与LVMI的降低有关。
作者 华鹏炯
出处 《现代实用医学》 2011年第4期412-413,共2页 Modern Practical Medicine
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