摘要
对遗传性痉挛性截瘫一家系6代98人进行了遗传学调查。其中19例均表现典型的临床症状。并对2例作肌电图检查显示锥体束损害征,对存活的患者进行染色体G显带分析,结果无显著异常。据系谱分析,该疾病符合常染色体显性遗传方式。
A family with 98 persons in 6 generations, was investigated. Nineteen of them were affectived with hereditary spastic paraplegia and have typical clinical symptoms, Two cases were examined by electromyogram and show syndrom of damaged pyramidal tract. The cases alive were studied with chromosome G band, no abnormality appears on anybody. With pedigree analysis, the genetic mode of the disease in the family are autosomal dominant inheritance.
出处
《潍坊医学院学报》
1990年第2期39-40,共2页
Acta Academiae Medicinae Weifang
关键词
遗传性痉挛性
截瘫
遗传学分析
hereditary spastic paraplegia
electromyogram
autosomal dominant inheritance disease
