摘要
蓝氏贾第鞭毛虫是一种重要的致病性寄生虫,人体感染后主要引起腹泻和营养不良等症状。作为一种源真核生物,其基因表达调控机制可能与其他真核生物有较大的区别。本文从蓝氏贾第虫鞭毛虫启动子、转录因子、转录后调节、翻译起始和表观遗传学等方面,对贾第虫基因表达调控的研究进展进行综述。
Giardia lamblia is an important human pathogen that causes diarrhea and malnutrition.As a late-bran-ching eukaryote,G.lamblia may have special mechanisms for regulating gene expression which differ from other eukar-yotes.In this paper,the mechanisms that governing regulation of G.lamblia gene expression,such as promoters,transcription factors,transcriptional regulation,translation initiation and epigenetic mechanisms are summarized.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
2011年第2期138-141,共4页
Chinese Journal of Parasitology and Parasitic Diseases
基金
国家自然科学基金(No.30872207
30901253)~~
