摘要
目的:探讨64层CT评价冠状动脉粥样硬化斑块性质与冠脉狭窄程度之间的相关性。方法:36例疑诊为冠心病患者行64层冠状动脉CT血管成像(CCTA)及冠状动脉血管造影(CAG)检查,以CAG为标准评价CCTA诊断冠脉狭窄程度的准确性,并诊断冠状动脉粥样硬化斑块性质,分析其与经CAG确诊的冠脉狭窄程度之间有无统计学意义。结果:36例患者中共检出105个斑块。冠脉轻度狭窄以钙化斑块引起为主,冠脉中度狭窄和重度狭窄以混合斑块引起为主。CCTA诊断冠状动脉钙化斑块与管腔轻度狭窄、混合斑块与中重度管腔狭窄存在相关性。结论:64层CCTA可在诊断冠脉狭窄的同时无创性评价斑块性质,可及时发现冠脉中脂质成分丰富的斑块,以便尽早及时给予临床干预,可降低急性冠脉综合征发生率。
Objective：To evaluate the correlation between the nature of atherosclerotic plaque and the degree of stenosis of coronary artery（CA） using 64-slice CT.Methods：36 patients with suspected coronary atherosclerotic heart disease underwent 64-slice CT coronary angiography（CCTA） and coronary artery angiography（CAG）.CAG findings were used as the standard to evaluate the accuracy of CCTA in diagnosing the degree of stenosis of CA,and the nature of atherosclerotic plaque was studied as well.Whether there was statistical significance between the nature of plaque and the degree of CA stenosis was studied as well.Results：A total of 105 plaques were detected in CA of these 36 patients.Mild CA stenosis was mainly coused by calcified plaque,and significant（moderate and serious） stenosis was mainly caused by mixed plaque.There was correlation between calcified plaque diagnosed by CCTA and mild CA stenosis,as well as between mixed plaque and significant CA stenosis.Conclusion：Nature of CA plaque could be concurrently evaluated non-invasively while diagnosing CA stenosis with CCTA using 64-slice CT.Early clinical intervention provided prevention of acute coronary syndrome by timely detection of lipid-rich CA plaque.
出处
《放射学实践》
北大核心
2011年第4期414-418,共5页
Radiologic Practice
基金
江西省卫生厅科技计划课题(20073065)
关键词
冠心病
冠状动脉狭窄
冠状动脉粥样硬化斑块
体层摄影术
X线计算机
Coronary atherosclerotic heart disease
Coronary artery stenosis
Coronary artery atherosclerotic plaque
Tomography
X-ray computed
