摘要
目的应用实时三维超声心动图评价风湿性心脏瓣膜病瓣膜置换术前、后右心功能的变化,探讨其临床价值。方法应用GE VIVID 7.0采集30例风湿性心脏瓣膜病患者瓣膜置换术前及术后右室全容积图像。适用Tom Tec 4D RV-analysis软件,结合半自动心内膜探测系统获取右室舒张末容积(RVEDV)、收缩末容积(RVESV)、搏出量(SV)、射血分数(RVEF)及右室整体时间-容积曲线。并用配对t检验及直线相关分析进行对比研究手术前后右室功能的变化。结果术前RVEDV、RVESV、RVEF与术后差异均有统计学意义(P<0.05)。术后RVEDV、RVESV较术前有明显减小,以RVESV减少最为显著,RVEF明显增加(P<0.05)。相关分析显示:RVEDV手术前后相关性高于RVESV(r=0.799,P<0.0001),提示术前右心功能不全主要与舒张末容积增大有关。结论实时三维超声心动图能够精确量化右心室功能,为临床正确判断风湿性心脏瓣膜病瓣膜置换前后右心室功能、观察疗效、判断预后等提供可靠的客观依据。
Objective To compare the pre-and post-operative right ventricular functions of rheumatic heart disease with real-time three-dimensional echocardiography.Methods Thirty patients with rheumatic heart disease,the pre-and post-operative right ventricular of the full volume images were performed by using GE ViVid 7.0 with X3-1 probe.The right ventricular global time-volume curve and end-diastolic volume（RVEDV）,end-systolic volume（RVESV）,ejection fraction（RVEF） were obtained by the off-line Tom Tec software 4D LV-Analysis system and primary manual tracking with semiautomated border detection.The outcomes were assessed with paired t-test and pearson correlation coefficient analysis.Results Compared with pre-operative right ventricular end-diastolic and end-systolic volumes,stroke volume,ejection fraction;post-operative right vetricular end-diastolic and end-systolic volumes obviously decreased after surgical valve replation（P0.05）.Accordingly,compared with pre-operative stroke volume,ejection fraction,post-operative markedly increased（P0.05）.Correltions of the pre-and post-operative right ventricular end-diastolic volume were higher than those of the pre-and post-operative right ventricular end-systolic volume（r=0.799,P0.0001）.The results indicated that per-operative right ventricular funtion correlation with the right ventricular end-diastolic volume.Conclusion RT-3DE can provide quantitative information of cardiac function for pre-and post-operative follwing-up Valve replation of Rheumatic heart disease.
出处
《安徽医学》
2011年第4期420-422,共3页
Anhui Medical Journal
基金
安徽医科大学中青年教师科研基金(编号:2010XKJ104)
关键词
实时三维超声心动图
风湿性心脏瓣膜病
右心功能
Real-time three-dimensional echocardiography
Rheumatic heart disease
Right ventricular function
