摘要
76例发病≤6h的急性心肌梗死（AMI）患者随机分为2组，根据常规心电图初始ST段的抬高预计和最后QRS改变估计心肌死范围（MIS），观察尿激酶对MIS的影响。结果表明：MIS在对照组治疗前后差异无显著性意义（P＞0．05）；在尿激酶组治疗前后差异有显著性意义（P＜0．01）；2组MIS变化百分比差异有显著性意义（P＜0．01）。其中尿激酶组未通亚组治疗前后MIS差异无显著性意义（P＞0．05），再通亚组治疗前后MIS差异有显著性意义（P＜0．01）。在两组未通病例中MIS变化百分比差异有显著性意义（P＜0．05）。提示尿激酶溶栓治疗可显著减少MIS，挽救缺血濒死的心肌，这一效果在冠状动脉（冠脉）两通的病列中尤为突出，对冠脉未通病例也有一定作用。
To inquire into the influence on MIS in AMI receiving thrombolysis by Urokinase. The 76 cases of AMI that frist onset in 6h were randomyly diveded into two groups,and to predictive MIS depen-dent on elavation of ST segment lof ECG and QRS changes. The change of MIS in the control group predicted not obviously difference (P>0.05),but there were obviously difference in the Urokinase group (P<0.01). There are certain predictive Values for MIS in AMI after thrombolysis by Urokinase.
出处
《海峡药学》
1999年第3期65-67,共3页
Strait Pharmaceutical Journal
