摘要
间充质干细胞（MSCs）可以成功地从所有哺乳动物组织细胞内分离出来，它的多向分化潜能在再生医学中有很大应用潜力。随着对MSCs的生物学特征、MSCs与其周围内环境之间的相互作用、MSCs归巢的分子调节机制及多向分化能力的深入研究，MSCs将作为细胞修复或外源性基因转染和表达的载体在临床试验中发挥重要作用。
Mesenchymal stem cells （MSCs）have been successfully isolated from almost all tissues in mammals, and their multi- lineage differentiation ability leads to the attractive application of MSCs in regenerative medicine. More understanding of the biological characteristics of MSCs, the interaction between MSCs and the local environment, the molecules regulating MSC homing and differentiation have been achieved, which will benefit the effective clinical trials using MSCs as repair cells and/or vehicles for exogenous genes.
出处
《国际外科学杂志》
2011年第5期331-334,共4页
International Journal of Surgery
基金
南京军区重点课题（No.082029）
关键词
间充质干细胞
细胞修复
Mesenchymal stem cells
Repair cells
