摘要
目的:建立测定利培酮分散片中利培酮含量的方法。方法:采用紫外分光光度法。溶剂为无水乙醇,在279nm波长条件下测定利培酮分散片中利培酮的含量。结果:利培酮检测浓度在6.12～30.6μg·mL-1范围内与吸光度呈良好的线性关系(r=0.9999);平均回收率为100.31%,RSD=0.54%(n=9)。结论:本法准确、可靠、重复性好,可用于利培酮分散片的质量控制。
OBJECTIVE： To establish the method for the content determination of Risperidone dispersible tablet. METHODS： UV spectrophotometry was adopted using absolute alcohol as solvent. The detection wavelength was set at 279 nm. RESULTS： The linear range of risperidone was 6.12～30.6 μg·mL-1 （r=0.999 9） with an average recovery of 100.31%（RSD=0.54%, n=9）. CONCLUSION： The method is accurate, reliable and reproducible for the content determination of Risperidone dispersible tablet.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第20期1906-1908,共3页
China Pharmacy
关键词
利培酮分散片
含量测定
紫外分光光度法
Risperidone dispersible tablet
Content determination
UV spectrophotometry
