摘要
目的探讨长期饮酒者肝纤维化四项检测结果及临床意义。方法回顾性分析2009年12月～2010年7月在该院进行体检的456例患者的临床资料,236例长期饮酒者(10年以上酒龄)作为观察组,220例不饮酒者作为对照组,比较两组的血清透明质酸(HA)层黏连蛋白(LN)、Ⅳ型胶原(CⅣ)、Ⅲ型前胶原(PCⅢ)的含量。结果观察组的HA、LN、CIV、PCⅢ含量均明显高于对照组,组间差异均有统计学意义(均P<0.05)。结论长期饮酒者肝纤维4项(HA、LN、CIV、PCⅢ)检测结果均明显高于正常值,能够反映人体的健康状态,值得临床关注。
【Objectives】To discuss the testing results and clinical significance of liver textile fiber four of chronic drinkers.【Methods】From December 2009 to July 2010 in our hospital,the clinical data of 456 cases with medical examination were retrospectively analyzed,236 cases of long-term drinkers as the observa-tion group,220 cases with non-drinkers as the control group,the serum content of hyaluronic acid（HA）,laminin（LN）,collagen type Ⅳ CⅣ） and procollagen type Ⅲ PCⅢ） of two groups were compared.【Results】 The serum content of HA,LN,CIV,PC Ⅲ of the observation group were significantly higher than the control group,there were significant differences between two groups（all P 0.05）.【Conclusion】The serum content of HA,LN,CIV,PC Ⅲ of long-term drinkers were significantly higher than normal test results,can reflect the health status of the human body,is worthy of clinical attention.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2011年第11期1416-1418,共3页
China Journal of Modern Medicine
关键词
透明质酸
层黏连蛋白
Ⅳ型胶原
Ⅲ型前胶原
hyaluronic acid（HA）
laminin（LN）
collagen type Ⅳ（CⅣ）
procollagen type Ⅲ（PCⅢ）
