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聚乙二醇干扰素α联合核苷(酸)类似物治疗慢性乙型肝炎研讨会纪要 被引量：5

Summary of the expert forum on Peg-IFNα combined with NUCs for chronic hepatitis B
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摘要 2010年9月,《中华传染病杂志》、《中华肝脏病杂志》、《中国病毒病杂志》联合召开了慢性乙型肝炎（乙肝）聚乙二醇干扰素α（Peg-IFNα）联合核苷（酸）类似物（NUCs）治疗研讨会。根据目前国内外的研究结果, Summary of the expert forum on Peg-IFNαcombined with NUCs for chronic hepatitis B Corresponding authors： Zhuang Hui,Department of Microbiology,Peking University Health Science Center,Beijing 100191,China.E-mail： zhuangbmu@ 126.com;WENG Xin-hua,Department of Infectious Disease,Huashan Hospital,Fudan University,Shanghai 200040,China.E-mail： wengxinhua@ fudan.edu.cn
作者 庄辉 翁心华
机构地区 北京大学医学部病原生物学系 复旦大学附属华山医院感染科
出处 《中国病毒病杂志》 CAS 2011年第2期143-146,共4页 Chinese Journal of Viral Diseases
关键词 聚乙二醇干扰素Α 核苷(酸)类似物 联合治疗 Peg IFN-α Neucleos（t）ides Combination therapy
分类号 R512.62 [医药卫生—内科学]
  • 相关文献

参考文献18

  • 1万谟彬,翁心华.干扰素治疗慢性乙型肝炎专家建议[J].中华传染病杂志,2007,25(10):577-583. 被引量：48
  • 2Liaw YF,,Chu CM.Hepatitis B virus infection. The Lancet . 2009 被引量：1
  • 3Fattovich G,,Bortolotti F,Donato F.Natural history of chronichepatitis B:special emphasis on disease progression and prog-nostic factors. Journal of Hepatology . 2008 被引量：1
  • 4Sung JJ,Tsoi KK,Wong VW,et al.Meta-analysis:treat mentof hepatitis Binfection reduces risk of hepatocellular carcinoma. Alimentary Pharmacology and Therapeutics . 2008 被引量：1
  • 5Ma W,Zhou B,Ao F,et al.Higher sustained post-treat mentresponse following peginterferon alpha-2a±adefovir comparedwith adefovir monotherapy in HBeAg positive patients. Hepatology . 2009 被引量：1
  • 6Takkenberg B,Zaaijer H,Weegink C,et al.Baseline HBsAglevelpredict HBsAg loss in chronic hepatitis B patients treated witha combination of peginterferon alpha-2a and adefovir:an inter-i manalysis. Hepatology . 2009 被引量：1
  • 7Cao Z,Zhang Y,Ma L,et al.Treat ment of HBeAg positiveCHBinfection with peginterferon alpha-2a[40KD]plus lami-vudine or adefovir for 96 weeks results in high rate of HBsAgclearance/seroconversion. Hepatology . 2010 被引量：1
  • 8Lau GKK,Marcellin P,Brunetto M,et al.On treat ment mo-nitoring of HBsAg levels to predict response to peginterferonalpha-2a in patients with HBeAg positive chronic hepatitis B. Journal of Hepatology . 2009 被引量：1
  • 9Wang J,Xu Y,Siqingtu N,et al.The efficacy of individualizedpeginterferon alpha-2a therapy and its influence on histologicalresponse in the management of HBeAg-positive CHB patients. Hepatology . 2010 被引量：1
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二级参考文献9

  • 1慢性乙型肝炎防治指南[J].中华传染病杂志,2005,23(6):421-431. 被引量：824
  • 2Lok AS, McMahon BJ. Chronic hepalitis B. Hepalology, 2007, 45:507-539. 被引量：1
  • 3Cooksley WG, Piratvisuth T, Lee SD, et al. Peginterferon alpha-2a (40 kDa) : an advance in the treatment of hepatitis Be antigen-positive chronic hepatitis B. J Viral Hepat, 2003, 10 : 298-305. 被引量：1
  • 4Lau GK, Piratvisuth T, Luo KX, et al. Peginterferon Alfa 2a HBeAg-Positive Chronic Hepatitis B Study Group. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B. N Egngl J Med, 2005, 352:2682-2695. 被引量：1
  • 5Marcellin P, Lau GK, Bonino F, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med, 2004, 351:1206-1217. 被引量：1
  • 6Lau GK, Piratvisuth T, Luo KX, et al. Durability of response and occurrence of late response to peginterferon alpha-2a(40KD)[PEGASYS] one year post-treatment in patients with HBeAg-positive chronic hepatitis B. J Hepatology, 2006, 44 Suppl 2:S23-S24. 被引量：1
  • 7Marcellin P, Bonino F, Lau GK, et al. Virological and biochemi-cal response in patients with HBeAg-negative CHB treated with peginterferon alfa-2a(40 kD) + lamivudine: 3-year follow-up resuits. J Hepatology, 2007, 46 Suppl 1:S25-S26. 被引量：1
  • 8Di Bisceglie AM, Lai CL, Gane E, et al. Telbivudine Globe Trial : Maximal early HBV suppression is predictive of optimal two-year efficacy in nucleoside-treated hepatitis B patients. Hepatology, 2006, 44(Suppl):230A 231A. 被引量：1
  • 9Hoofnagle JH, Doo E, Liang TJ, et al. Management of hepa titis B: summary of a clinical research workshop. Hepatology, 2007, 45:1056-1075. 被引量：1

共引文献47

同被引文献38

  • 1中华医学会肝病学分会,中华医学会感染病学分会.慢性乙型肝炎防治指南[J].中华流行病学杂志,2006,27(1):79-88. 被引量：389
  • 2Flink HJ,van Zonneveld M,Hansen BE,陆伟（摘译）,张占卿（审校）.聚乙二醇化干扰素a-2b治疗HBeAg阳性慢性乙型肝炎：HBsAg转阴与HBV基因型相关[J].世界感染杂志,2006,6(4):357-357. 被引量：46
  • 3Maddrey WC. Hepatitis B: an important public health issue [ j] . JMed Virol, 2000, 61(3):362-366. 被引量：1
  • 4McMahon BJ. Epidemiology and natural history of hepatitis B [J].Semin Liver Dis, 2005(Suppl 1):S3-S8. 被引量：1
  • 5Lau GK, Piratvisuth T, Luo KX, et al. Peg-interferon alfa-2a,lamivudine and the combination for HBeAg-positive chronichepatitis B [J] . N Eng J Med, 2005, 352(26):2682-2695. 被引量：1
  • 6Marcellin P, Brunetto M, Bonino F, et al. In patients with HBeAg-negative chronic hepatitis B HBsAg serum levels early duringtreatment with peginterferon alfa-2a predict HBsAg clearance 4years post-treatment [EB/OL] . [2015-12-01 ] . http://natap.org/2008/AASLD/AASLD_54.htm. 被引量：1
  • 7Tatulli I,Francavilla R, Rizzo GL, et al. Lamivudine and alpha-interferon in combination long term for precore mutant chronichepatitis B [J] . J Hepatol, 2001, 35(Suppl 1):A59. 被引量：1
  • 8Takkenberg B, Zaaijer H, Weegink C, et al. Baseline HBsAg levelpredict HBsAg loss in chronic hepatitis B patients treated with acombination of peginterferon alpha-2a and adefovir: an interimanalysis [J] . J Hepatol, 2009, 50(Suppl 1):S8. 被引量：1
  • 9Janssen HL, van Zonneveld M, Senturk H, et al. Pegylatedinterferon alfa-2b alone or in combination with lamivudine forHBeAg-positive chronic hepatitis B: a randomised trial [J].Lancet, 2005,365(9454):123-129. 被引量：1
  • 10Flink HJ, Sprengers D, Hansen BE, et al. Flares in chronic hepatitisB patients induced by the host or the virus Relation to treatmentresponse during peg-interferon a -2b therapy [J] . Gut, 2005,54(11):1604-1609. 被引量：1

引证文献5

二级引证文献15

中国病毒病杂志
2011年 第2期

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