期刊文献+

子痫前期胎儿生长受限危险因素的Logistic回归分析 被引量:8

Logistic regression analysis of fetal growth restriction in pregnancy with preeclampsia
下载PDF
导出
摘要 目的:研究子痫前期胎儿生长受限的危险因素,为临床预防子痫前期胎儿宫内生长受限提供理论依据。方法:将136例子痫前期孕妇分娩的新生儿按出生体重分为小于胎龄儿(SGA)组(n=43)和非SGA组(n=93),对两组的临床症状和相关特征因素进行分析,找出导致胎儿宫内生长受限的危险因素。结果:导致子痫前期的胎儿宫内生长受限的危险因素有母亲吸烟(P=0.039,OR=11.112)、低蛋白血症(P=0.041,OR=4.876)、脐带血流改变(P=0.006,OR=9.217)、胎盘异常(P=0.043,OR=4.937)。结论:母亲吸烟、低蛋白血症、脐带血流改变、胎盘异常是子痫前期胎儿宫内生长受限的危险因素。 Objective: To study the risk factors of growth restriction of the preeclampsia fetuses and provide the theoretical basis to clinical prevention of the growth restriction in preeclampsia fetuses. Methods: One hundred and thirty-six neonates delivered by preeclampsia mothers were divided into two group according to the birth weight: small gestation age (SGA) group (n =43 ) and non-SGA group (n = 93 ). The clinical symptoms and related char- acteristic factors were analyzed to find the risk factors leading to fetal growth restriction. Results: Factors which in- creased the risk of growth restriction in the preeclampsia fetuses were smoking during pregnancy (P = 0. 039, OR = 11. 112), hypoproteinemia (P = 0. 041, OR = 4. 876), umbilical cord blood flow change (P = 0. 006, OR = 9. 217), abnormal placenta (P =0. 043, OR =4. 937). Conclusions: Maternal smoking, hypoproteinemia, um- bilical cord blood flow change and abnormal placenta are the risk factors of fetal growth restriction.
作者 陈红
出处 《东南大学学报(医学版)》 CAS 2011年第2期346-349,共4页 Journal of Southeast University(Medical Science Edition)
关键词 子痫前期 胎儿生长受限 危险因素 LOGISTIC回归分析 preeclampsia fetal growth restriction risk factors
  • 相关文献

参考文献12

  • 1SIBAI B M.Diagnosis and management of gestational hypertension and preeclampsia[J].Obstet Gynecol,2003,102(1):181-192. 被引量:1
  • 2LARS J,VATTEN M D,KJEL A,et al.Preeclampsia and fetal growth[J].Bstetrics & Gynecology,2000,96(6):950-955. 被引量:1
  • 3NESS R B,ROBERTS J M.Heterogeneous causes constituting the single syndrome of preeclampsia:a hypothesis and its implications[J].Am J Obstet Gynecol,1996,17(5):1365-1370. 被引量:1
  • 4乐杰.妇产科学[M].北京:人民卫生出版社,2005.184-185. 被引量:530
  • 5TANG C H,WU C S,LEE T H et al.Preeclampsia-eclampsia and the risk of stroke among peripartum in Taiwan[J].Stroke,2009,40(4):1162-1168. 被引量:1
  • 6ENGEL S M,JANEVIC T M,STEIN C R,et al.Maternal smoking,preeclampsia,and infant health outcomes in New York City,1995-2003[J].Am J Epidemiol,2009,169(1):33-40. 被引量:1
  • 7RASMUSSEN S,LRGENS L M.History of fetal growth restriction is more strongly associated with severe rather than milder pregnancy-induced hypertension[J].Hypertension,2008,51(4):1231-1238. 被引量:1
  • 8QUINTON A E,COOK C M,PEEK M J.The relationship between cigarette smoking,endothelial function and intrauterine growth restriction in human pregnancy[J].BJOG,2008,115(6):780-784. 被引量:1
  • 9VOGT ISAKSEN C.Maternal smoking,intrauterine growth restriction,and placental apoptosis[J].Pediatr Dev Pathol,2004;7(5):433-442. 被引量:1
  • 10CNATTINGIUS S,MILLS J L,YUEN J.The paradoxical effect of smoking in preeclamptic pregnancies:smoking reduces the incidence but increases the rates of perinatal mortality,abruptio placentae,and intrauterine growth restriction[J].Am J Obstet Gynecol,1997,177(1):156-1561. 被引量:1

共引文献529

同被引文献75

  • 1应豪,王德芬.孕28至32周重度妊高征的期待治疗[J].现代妇产科进展,2004,13(6):449-452. 被引量:57
  • 2杨孜,王伽略,黄萍,石凌懿,李蓉,叶蓉华,陈蕾.重度子痫前期临床发病类型及特点与围产结局的关系[J].中华妇产科杂志,2006,41(5):302-306. 被引量:155
  • 3Granger JP, Alexander BT, Bennett WA, et al. Pathophysiology of pregnancy-induced hypertension. Am J Hypertens, 2001, 141:178S-185S. 被引量:1
  • 4Wikstr6m AK, Larsson A, Eriksson UJ, et al. Placental growth factor and soluble FMS-like tyrosine kinase 1 in early- onset and late-onset preeclampsia. Obstet Gyneeol, 2007, 109: 1368-1374. 被引量:1
  • 5Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci, 2001, 114:853-865. 被引量:1
  • 6Wang A, Rana S, Karumanchi SA. Preeclampsia: the role of angiogenic factors in its pathogenesis. Phsiology(Bethesda), 2009, 24: 147-158. 被引量:1
  • 7Maynard SE, Min JY, Merchan J, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFltl) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J ClinInvest, 2003, 111: 649-658. 被引量:1
  • 8Eremina V, Jefferson JA, Kowalewska J, et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med, 2008, 358: 1129-1136. 被引量:1
  • 9Foster RR. The importance of cellular VEGF bioactivity in the development of glomerular disease. Nephron Exp Nephrol, 2009, 113: e8-e15. 被引量:1
  • 10Maharaj AS, D' Amore PA. Roles for VEGF in the adult. Microvasc Res, 2007, 74:100-113. 被引量:1

引证文献8

二级引证文献47

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部