摘要
目的:研究子痫前期胎儿生长受限的危险因素,为临床预防子痫前期胎儿宫内生长受限提供理论依据。方法:将136例子痫前期孕妇分娩的新生儿按出生体重分为小于胎龄儿(SGA)组(n=43)和非SGA组(n=93),对两组的临床症状和相关特征因素进行分析,找出导致胎儿宫内生长受限的危险因素。结果:导致子痫前期的胎儿宫内生长受限的危险因素有母亲吸烟(P=0.039,OR=11.112)、低蛋白血症(P=0.041,OR=4.876)、脐带血流改变(P=0.006,OR=9.217)、胎盘异常(P=0.043,OR=4.937)。结论:母亲吸烟、低蛋白血症、脐带血流改变、胎盘异常是子痫前期胎儿宫内生长受限的危险因素。
Objective: To study the risk factors of growth restriction of the preeclampsia fetuses and provide the theoretical basis to clinical prevention of the growth restriction in preeclampsia fetuses. Methods: One hundred and thirty-six neonates delivered by preeclampsia mothers were divided into two group according to the birth weight: small gestation age (SGA) group (n =43 ) and non-SGA group (n = 93 ). The clinical symptoms and related char- acteristic factors were analyzed to find the risk factors leading to fetal growth restriction. Results: Factors which in- creased the risk of growth restriction in the preeclampsia fetuses were smoking during pregnancy (P = 0. 039, OR = 11. 112), hypoproteinemia (P = 0. 041, OR = 4. 876), umbilical cord blood flow change (P = 0. 006, OR = 9. 217), abnormal placenta (P =0. 043, OR =4. 937). Conclusions: Maternal smoking, hypoproteinemia, um- bilical cord blood flow change and abnormal placenta are the risk factors of fetal growth restriction.
出处
《东南大学学报(医学版)》
CAS
2011年第2期346-349,共4页
Journal of Southeast University(Medical Science Edition)