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来氟米特对儿童难治性肾病综合征临床观察 被引量:8

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摘要 目的:观察来氟米特对儿童难治性肾病综合征治疗效果。方法:对27例儿童难治性肾病综合征分为激素抵抗型9例,激素依赖型14例,频复发型4例,分别给予来氟米特1mg/kg,每日1次口服,连续3d后改为0.2~0.4mg/kg,每日1次,泼尼松2mg·kg-1.d-1,逐渐减至适当剂量维持或停用。结果:治疗前和治疗6个月后血白蛋白(P=0.0002)和24h尿蛋白(P<0.0001)明显改善,27例儿童难治性肾病综合征治疗后部分缓解7例(25.93%),完全缓解12例(44.44%),总缓解率70.37%。在微小病变和非微小病变之间,差异具有统计学意义(P<0.05)。结论:来氟米特对改善儿童难治性肾病综合征具有一定效果。
出处 《中国中西医结合肾病杂志》 2011年第2期154-155,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
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