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血糖水平对急性冠状动脉综合征患者预后的影响

Impacts of blood glucose levels on prognosis of patients with acute coronary syndrome
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摘要 目的 探讨入院时空腹血糖水平对急性冠状动脉综合征(ACS)患者预后的影响.方法 对307例ACS患者进行回顾性分析,按照术前空腹血糖(FBS)水平分为3组:A组FBS<5.6mmol/L,B组5.6≤FBS<6.1mmol/L,C组FBS≥7.0mmol/L.对3组患者的基础临床资料及30d内心力衰竭、全因病死率、新发生的心律失常发生率进行比较分析.结果 不同空腹血糖水平ACS患者其高血压、高血脂的发生率差异均无统计学意义(均P >0.05),B、C两组与A组比较急性心肌梗死和糖尿病的发生率增高(均P<0.01) B、C两组与A组比较多支病变增加,植入支架数明显增多(P<0.05或0.01),C组与A组比较B2、C型病变增多(P<0.05) 随着血糖水平的增高,B、C两组与A组比较心力衰竭、全因病死率明显增多(均P<0.01),心律失常发生率也增高(均P<0.05).结论 空腹血糖升高提示ACS患者预后不良. Objective To investigate the association between the fasting blood glucose levels and the incidence of major adverse cardiovascular events (MACE) for acute coronary syndrome (ACS) patients in 30 days. Methods Total 307 ACS patients admitted to hospital from July 2003 to February 2010 were enrolled in this prospective study. Based on fasting blood glucose (FBS) levels, 307 patients were divided into 3 groups: group A (FBS〈5.6mmol/L), group B (5.6 ≤FBS〈6.1mmol/L), group C (FBS ≥7.0mmol/L). The incidence of MACE, including heart failure, all-cause mortality and new arrhythmia in 30 days was analyzed among these three groups. Results The number of branches with coronary arteriopathy in group B and C was more than that of group A significantly (P 〈0.05 or 0.01). The incidence of heart failure, all-cause mortality and new arrhythmia within 30 days in group B and C was higher than that of group A significantly (P〈0.05 and 0.01). Conclusion Fasting hyperglycemia indi- cates worse outcome in ACS.
出处 《浙江医学》 CAS 2011年第4期523-524,528,共3页 Zhejiang Medical Journal
关键词 急性冠状动脉综合征 血糖 预后 Acute coronary syndrome Blood glucose Prognosis
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