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地塞米松治疗外伤性蛛网膜下腔出血致严重头痛临床疗效观察 被引量:1

A comparison study on patients with headache after tSAH with hexadecadrol
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摘要 目的:观察地塞米松治疗外伤性蛛网膜下腔出血致严重头痛疗效。方法:将104例外伤性蛛网膜下腔出血(Traumatic subarachnoid hemorrhage,tSAH)后严重头痛患者随机分为治疗组52例和对照组各52例,治疗组采用静脉滴注地塞米松2.5~5.0 mg,2次/d;对照组给予口服布洛芬胶囊,餐前顿服0.3 mg,2次/d,两组均连用10 d,观察疗效。结果:治疗组总有效率94.2%,对照组总有效率61.5%,两组总有效率比较差异有统计学意义(P〈0.05)。结论:采用小剂量地塞米松静脉推注治疗外伤性蛛网膜下腔出血后严重头痛疗效明显优于对照组布洛芬,疗效显著且安全可靠。 Objective To observe the effect of hexadecadrol on severe headache induced by Traumatic subarachnoid hemorrhage(tSAh).Methods 104 patients with severe headache induced by tSAH were randomly divided into two groups:treatment group(n=52) and control group(n=52).The treatment group was treated with intravenous drip of hexadecadrol injection(2.5~5.0 mg,twice per day),and the control group was treated with ibuprofen capsules(orally taken before food,twice per day) for 10 days together with the treatment group.Results Statistical significance was detected in the treatment group and control group with total effective rates of 94.2% and 61.5%,respectively(P0.05).Conclusion Low-dose intravenous injection of hexadecadrol showed significant effect and higher safety on the patient with severe headache induced by tSAH compared with ibuprofen capsules group.
机构地区 陕西省核工业
出处 《吉林医学》 CAS 2011年第11期2137-2138,共2页 Jilin Medical Journal
关键词 地塞米松 布洛芬 外伤性蛛网膜下腔出血 头痛 治疗 tSAH Headache Hexadecadrol Treatment
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  • 1刘佰运,王忠诚.炎症反应与慢性脑血管痉挛[J].国外医学(神经病学.神经外科学分册),1993,20(5):231-233. 被引量:8
  • 2王向宇.蛛网膜下腔出血继发脑血管痉挛的病理机制新进展[J].国外医学(脑血管疾病分册),1994,2(3):161-164. 被引量:67
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33008
  • 4刘佰运,王忠诚,吴建中,苏敏成,李佑祥,孙异临.硫唑嘌呤与甲基强的松龙防治慢性脑血管痉挛的实验研究[J].中华医学杂志,1996,76(10):774-776. 被引量:3
  • 5Johshita H,Ksaaelln F,Sasaki T,et al.Biphasic constriction of rabbit basilar artery following experimental subarachnoid hemorrhage:a morphometric study,Surgical neurology,1992,vol.37,no.2,pp.106-114. 被引量:1
  • 6Kataoka K, Taneda M, Asai T,et al. Structural fragility and inflammatory response of ruptured cerebral aneurysms. A comparative study between ruptured and unruptured cerebral aneurysms [J]. Stroke, 1999,30(7): 1396 - 1401. 被引量:1
  • 7Sajanti J, Bjorkstrand AS, Finnila S, et al. Increase of collagen synthesis and deposition in the arachnoid and the dura following subarachnoid hemorrhage in the rat [ J ]. Biochim Biophys Acta,1999,1454(3) :209 - 216. 被引量:1
  • 8Julow J. The influence of dexamethasone on subarachnoid fibrosis after subarachnoid haemorrhage. Scanning electron microscopic study in the dog[J]. Acta Neurochir (Wien), 1979,51(1 -2):43-51. 被引量:1
  • 9German JW, Gross CE, Giclas P, et al . Systemic complement depletion inhibits experimental cerebral vasospasm [ J]. Neurosurgery, 1996,39(1): 141 - 146. 被引量:1
  • 10Massicotte EM, Del Bigio MR. Human arachnoid villi response to subarachnoid hemorrhage: possible relationship to chronic bydrccephalus[ J ]. Neurosurg, 1999,91 ( 1 ) : 80 - 84. 被引量:1

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