摘要
目的探讨输血相关急性肺损伤的临床表现、诊断和治疗。方法报告输血相关急性肺损伤2例并对相关文献进行复习。结果输血相关急性肺损伤是一种输血引起的急性呼吸窘迫综合征,报告的2例患者均发生在输血后6 h内,表现为急性呼吸窘迫、双肺水肿、低氧血症、肺部弥漫的毛玻璃样影。通常需要吸氧、机械通气等治疗。结论如果患者在输血后出现迅速进展的低氧血症,应考虑本病,早期诊断和治疗是提高生存率的关键。
Objective To explore the clinical manifestation,diagnosis,therapy of transfusion related acute lung injury（TRALI）.Methods Two cases of TRALI were reported and the literatures were also reviewed.Results TRALI is an acute respiratory distress syndrome due to transfusion,two reported patients appeared within 6 hours of transfusion of a plasma containing blood product,presented with acute respiratory distress,bilateral pulmonary edema and hypoxemia,diffuse ground-glass shadows on chest X-ray.Oxygen support and mechanical ventilation were usually required to treat the TRALI.Conclusion One should be alert to the occurrence of TRALI when rapidly progressive hypoxemia appeared after blood product transfusion,early diagnosis and quick treatment are the key to improving survival in these patients.
出处
《临床肺科杂志》
2011年第6期862-864,共3页
Journal of Clinical Pulmonary Medicine
关键词
肺损伤
输血相关肺损伤
输血
副反应
lung injuries
transfusion-related acute lung injury
transfusion
adverse reaction
