摘要
目的:观察芪蛭颗粒治疗下肢深静脉血栓形成(DVT)对血液流变学和血液动力学指标的影响。方法:选择100例住院病人,随机分为芪蛀颗粒治疗组和对照治疗组,观察两组病人用药前后血液流变学和血液动力学指标的变化。结果:(1)治疗组全血表观粘度(ηb)、血浆粘度(ηp)、红细胞压积(Hct)、血沉(ESR)、纤维蛋白原(Fg)等血液流变学指标较对照治疗组均明显下降(P<0.05);(2)芪蛭颗粒治疗组节段性静脉容积(SVC)、静脉最大回流量(MVO)、静脉回流速率(Ratio)、静脉压恢复时间(VRT)等血液动力学指标较对照治疗组均明显增加(P<0.05);(3)两组均未见明显出血性并发症。结论:芪蛭颗粒可通过改善血液流变学和血液动力学指标有效治疗DVT。
Objective:To observe influence of Qizhi granules on hemorheology and hemodynamic indexes in patients with lower extremity deep venous thrombosis(DVT).Method:100 patients with DVT were included and divided into two groups randomly,Qizhi granules,urokinase and aspirin,dipyridamole were given to the treatment group,except for Qizhi granules the control group was given the same remedy.The hemorheology indexes and hemodynamic indexes were compared after continuous treatment for 15 days according to the same criterions.Results:The hemorrheology indexes such as blood viscosity,plasma viscosity,erythrocyte etc.and hemodynamic indexes such as venous capacitance(SVC),second venous outflow(MVO),venous refill time(VRT)were significant difference(P<0.05).The treatment group was superior to that of control group.Conclusion:Qizhi granules can improve hemorheology and hemodynamic,which is an effective medicine for treatment of DVT.
出处
《微循环学杂志》
2011年第2期27-29,I0001,共4页
Chinese Journal of Microcirculation
