摘要
目的:探讨^(99m)Tc-MIBI SPECT对肺癌及纵隔转移淋巴结的术前评估价值。方法:对照50例“肺部阴影待查”患者术后病理与术前^(99m)Tc-MIBI SPECT显像结果,获取相关诊断试验指标。结果:^(99m)Tc-MIBI SPECT对肺癌和纵隔转移淋巴结的诊断敏感性、特异性、准确性分别为93％,50％,86％和81％,95％,88％。结论:^(99m)Tc-MIBI SPECT对术前诊断支气管肺癌并预测纵隔转移淋巴结有较高的应用价值,对手术中定向摘除转移淋巴结具有实际指导意义。
AIM: To evaluate the value of technetium-99m-methoxyisobutyl isonitrile (99mTc-MIBI) single-photon emission-computed tomography (SPECT) in diagnosis of lung cancer and in preoperative prediction of mediastinal metastasis lymph nodes. METHODS: After the chest image of 99mTc-MIBI SPECT, fifty patients (40M, 10F; age 56 a±11 a) diagnosed "lung field shadow" underwent the lung focus and mediastinal lymph nodes resection. As the golden standard, pathologic diagnosis was used to evaluate the role of preoperative 99mTc-MIBI SPECT. RESULTS: The sensitivity, specificity, and accuracy of 99mTc-MIBI SPECT were 93 % , 50 % , and 86 % , respectively in lung cancer and 81 % , 95 % , and 88 % , respectively in mediastinal metastasis lymph node. The results were also better than those of chest scan with CT, CONCLUSION: The 99mTc-MIBI SPECT is a useful and noninvasive method for diagnosing lung cancer and predicting mediastinal metastasis lymph nodes, which will guide the surgeon to resect the mediastinal metastasis lymph nodes.
出处
《中国药理学报》
CSCD
1999年第9期800-804,共5页
Acta Pharmacologica Sinica
关键词
肿瘤转移
肺肿瘤
纵隔肿瘤
淋巴瘤
CT
诊断
lung neoplasms
mediastinal neoplasms
lymph nodes
technetium compounds
single-photon emission-computed tomography
