摘要
目的探讨卵巢癌患者手术治疗前后血清。方法采用放射免疫分析法和酶联法对36例卵巢癌患者进行了手术治疗前后血清CA125、VEGF和IL-8水平检测,并与35名正常健康人作比较。结果卵巢癌患者在手术治疗前血清CA125、VEGF和IL-8水平非常显著地高于正常人组。手术治疗6个月后则与正常人比较无显著性差异(P>0.05)。结论卵巢癌的发生与发展与血清中CA125、VEGF和IL-8水平密切相关。
Objective To explore the clinical significance of changes of serum CA125,VEGF and IL-8 levels after operation treatment in patients with ovarian cancer.Methods Serum CA125,IL-8（with RIA）.VEGF（with ELISA） levels were measured in 36 patients with ovarian cancer both before and after operative treatment as well as in 35 controls.Results Before operative treatment the serum CA125,VEGF and IL-8 levels in patients were significantly higher than those in the controls（P0.01）.6 months after operative treatment,the serum CA125,VEGF and IL-8 levels in patients were not much different from those in the controls（P0.05）.Conclusion Serum levels of CA125,VEGF and IL-8 levels were closely related to the disease status in patients with ovarian cancer.
出处
《淮海医药》
CAS
2011年第3期219-220,共2页
Journal of Huaihai Medicine
关键词
卵巢肿瘤
糖类抗原-125
血管内皮生长因子
白细胞介素-8
Ovarian neoplasms
Carbohydrate antigen 125（CA125）
Vascular endothelial growth factor（VEGF）
Interleukin-8（IL-8）
