摘要
目的探讨头颈部肿瘤放疗中真菌感染的诊治疗效。方法回顾性分析14例头颈部肿瘤真菌感染病例的诊治过程及治疗方法。结果 8例患者均在接受治疗2-3 d后症状即有减轻、体温下降,7-10 d后症状基本消失,体温恢复正常,维持治疗1-3周后停药,随访2-6个月无复发;1例伴糖尿病、高血压者,在接受治疗的同时控制血糖、血压;2例在治疗前肝功能检查：谷丙转氨酶、谷草转氨酶均偏高,治疗后第2周后复查转氨酶有逐渐增高趋势,考虑患者临床上已基本痊愈,即予停药。结论真菌感染的治疗以抗真菌为主,可选用抗菌谱广、不良反应小的氟康唑、伊曲康唑等治疗。
OBJECTIVE To discuss the effect of diagnosis and treatment of fungal infections in head and neck cancer by radiotherapy.METHODS The diagnosis and the treatment were retrospectively analyzed in 14 patients with head and neck cancer fungal infections cases.RESULTS Totally 8 patients were treated after 2~3 d to reduce the symptoms that,the temperature droped,7~10 d after the symptoms disappeared,the body temperature returned to normal,maintained the therapy for 1 to 3 weeks after the withdrawal,followed up for 2 to 6 months without recurrence.1 case with diabetes,hypertension,while receiving treatment in internal medicine to help control blood sugar and blood pressure.2 patients were performed the liver function tests before the treatment：alanine aminotransferase,aspartate aminotransferase are high,the first 2 weeks after treatment has gradually increased after the review of aminotransferase trend has been basically considered clinically cured patients,withdrawal verdict.CONCLUSION The antifungal treatment is mainly the choice for fungal infection.Fluconazole and itraconazole,which are with broad antibacterial spectrum and less side effects,can be selected.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第9期1775-1776,共2页
Chinese Journal of Nosocomiology
关键词
头颈部肿瘤
放射治疗
真菌感染
Head and neck cancer
Radiotherapy
Fungal infection
