摘要
背景血压升高是中国人群脑卒中发病最重要的危险因素。降压治疗能显著减少脑卒中复发。目的了解中国非急性期缺血性脑卒中患者血压控制及降压药物使用情况,分析影响血压控制的因素。方法借助一项国际多中心临床试验在中国实施之际,对病史超过3月的缺血性脑卒中患者进行调查。利用电子问卷采集资料,进行统计描述和分析。结果 2007-06-2009-10期间,在中国14座城市共调查缺血性脑卒中患者6417名,平均年龄64岁。74%(4733)已知明确的高血压病史,其中20%未服用任何降压药物,仅21%(995)血压控制达标。血压控制率随服用降压药种类增多而逐渐增高(P<0.01)。合并糖尿病者血压控制率明显低于非糖尿病患者。合并心肌梗死或经皮冠状动脉介入治疗者血压控制率均高于无此病史者,服用他汀类药物或抗血小板药物的患者血压控制率高于不服药者(P<0.05)。1684例无高血压病史的患者中有60%血压升高。结论中国缺血性脑卒中患者血压控制情况距指南要求仍存在很大差距,加强其血压控制,将改善此类患者的预后。
Background Hypertension is the most important risk factor of stroke in Chinese people.Antihypertensive treatment can reduce recurrence of stroke considerably.Objective To investigate the blood pressure control and antihypertensive medication use in patients with established ischemic stroke and determine the factors influencing blood pressure control.Methods Patients with ischemic stroke were screened to consider participation in a clinical trial and information was collected about their disease history and medication use.Also with E-questionnaire,their blood pressure measurement,as well as body mass index and waist circumference,was recorded.Results Between June 2007 and October 2009,6417 patients with ischemic stroke from 14 cities in China were interviewed.Their mean age was 64 years.A history of hypertension was present in 4733（74%）patients,20% of whom took no antihypertensive drug,and only 995 patients（21%）reached the goal of blood pressure control according to current guidelines.The incidence of comorbid diabetes was associated with poorer blood pressure control（P0.01）.A history of myocardial infarction or previous coronary intervention was associated with better blood pressure control.So was the taking of anti-platelet agents or statins（P0.05）.Elevated blood pressure occurred in 1684（60%）patients without the history of hypertension.Conclusion A substantial proportion of patients with ischemic stroke have not reached the target blood pressure recommended by current guidelines.The prognosis of these patients should be improved by effective blood pressure control.
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2011年第3期246-250,共5页
Chinese Journal of Hypertension
关键词
高血压
缺血性脑卒中
治疗
现状调查
Hypertension
Ischemic stroke
Treatment
Cross-sectional study
