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内源性大麻素系统抗胶质瘤的作用机制 被引量:6

The mechanisms of endocannabinoid system anti-glioma
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摘要 内源性大麻素系统是近年来研究较为深入的一个脂质信号和神经调节系统,广泛参与了体内一些生理或病理过程的调节。大量的研究表明,内源性大麻素系统及其相关药物能在体内外实验中抑制胶质瘤的生长,深入研究内源性大麻素系统抗胶质瘤的作用机制对改善胶质瘤的化疗效果具有重要的临床意义。 In recent years,endocannabinoid system has been an intensively investigated lipid signaling and neuromodulatory system,which extensively involves in regulation of some physiological or pathological processes.A large number of researches demonstrate that endocannabinoid system and related agents inhibit the growth of glioma both in vitro and in vivo trials.Deeply investigating the mechanisms of endocannabinoid system anti-glioma is very significant for improving the chemotherapeutic efficacy of glioma.
出处 《临床肿瘤学杂志》 CAS 2011年第3期274-277,共4页 Chinese Clinical Oncology
关键词 大麻素 内源性大麻素系统 胶质瘤 胶质瘤干细胞 Cannabinoid Endocannabinoidsystem Glioma Glioma stem cells
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