摘要
目的:通过对19例儿童急性白血病合并侵袭性真菌感染病例分析,探讨伏立康唑治疗儿童白血病侵袭性肺部真菌感染的疗效及安全性。方法:回顾性分析19例肺部真菌感染患儿,全部病例均于诊断后给予伏立康唑治疗,轻症予伏立康唑口服(7 mg/kg.次,每12 h1次),重症予伏立康唑静点(7 mg/kg.次,每12h/次),治疗2周至2个月。结果:总有效率89%,毒副作用小,耐受性好,序贯性好。结论:伏立康唑是儿童白血病侵袭性肺部真菌感染的安全有效药物。
Objective：According to analyzing 19 cases of children with acute leuk emia and invasive fungal infections,the author tried to point out the efficacy and safety of the Voriconazole treatment of leukemia children with invasive pulm onary fungal infection. Methods：All patients after diagnosis were given Voricon azole treatment,the mild with voriconazole oral（7 mg/kg·h）,the severe with v oriconazole intravenous（7 mg/kg,once per 12 hours）,the treatment lasts 2 weeks or 2 mont hs. Results：The total efficiency is 89%,drug side effects were light,and Votiv onazole had good tolerance and sequential good. Conclusion：Voriconazole is safe and effective for teating leukemia children with invasive pulmonary fungal infe ction.
出处
《河南医学研究》
CAS
2011年第1期101-102,共2页
Henan Medical Research
关键词
伏立康唑
儿童白血病
肺部真菌感染
voriconazole
childhood leukemia
pulmonary fungal infection
