摘要
[目的]观察糖尿病病人注射重组人粒细胞刺激因子(G-CSF)后外周血白细胞峰值时间及不良反应。[方法]100例注射重组人粒细胞刺激因子糖尿病病人,每天在注射后的4个时间段采集血常规,观察不同时间的白细胞数值以及不良反应。[结果]白细胞峰值出现的时间第1天为注射后6 h、9 h;第2天～第4天为6 h;男女无差别,不同G-CSF注射剂量峰值无差异。第3天、第4天病人不良反应相对集中。[结论]临床医师可参考病人注射G-CSF后白细胞出现高峰的时间进行外周血采集。
Objective：To observe the peak time of peripheral blood leucocyte and adverse reactions in diabetic patients after injecting granulocyte-colony stimulating factor（G-CSF）.Methods：A total of 100 diabetic patients who accepted the injection of G-CSF were selected and they were collected the blood routine at 4 time points after the injection every day,then to observe WBC numerical value and adverse reactions at different time points.Results：The peak time of peripheral blood leucocyte was 6h and 9h after the injection at the first day;while 6h after the injection from the second day to the fourth day.There was no significant difference between men and women,and there was no significant difference in the peak time of different G-CSF injection dose.Patients＇adverse reactions were relative concentration at the third and fourth day.Conclusion：Clinicians can collecte the peripheral blood,with consulting the peak time of leucocyte present after injection of G-CSF Being.
出处
《护理研究（下旬版）》
2011年第4期1050-1051,共2页
Chinese Nursing Researsh
