摘要
目的分析原始神经外胚层瘤（pri mitive neuroectodermal tumor,PNET）的临床特点、诊断、治疗方法和预后。方法回顾性分析27例PNET患者的临床资料,其中19例行综合治疗,8例行非综合治疗。结果 27例患者均获随访,随访时间为8~65个月,总的生存期为6~63个月,中位生存期21个月。其中1年生存期为77.8%,2年生存期为48.1%,3年生存期25.9%。综合治疗中位生存期为29个月,非综合治疗中位生存期为14个月,2种治疗方法比较差异有统计学意义（P〈0.05）。结论 PNET是一种高度恶性肿瘤,好发于青少年,病理检查是可靠的诊断方法,预后较差,综合治疗可有效地提高患者生存率。
Objective To analyze the clinical characteristics,diagnosis,therapy and prognosis of primitive neuroectodermal tumor（PNET）.Methods The clinical data from 27 patients with PNET were analyzed retrospectively.Among the 27 patients,19 received combined therapy,and 8 received non-combined therapy.Results All patients were followed up for 8 to 65 months.The median overall survival was 21 months（range,6 to 63 months）,including 1 year survival of 77.8%,2 year survival of 48.1% and 3 year survival of 25.9%.Compared with patients receiving non-combined therapy,patients receiving combined therapy achieved a significant improvement in median survival（29 months vs 14 months,P0.05）.Conclusion PNET,a highly malignant tumor,occurs most often in young people.The pathological observation is a reliable method for diagnosis of PNET and the combined therapy can effectively improve the survival rate.The prognosis of PNET is very poor.
出处
《实用临床医学（江西）》
CAS
2011年第2期41-42,共2页
Practical Clinical Medicine
关键词
原始神经外胚层瘤
诊断
综合治疗
预后
primitive neuroectodermal tumor
diagnosis
combined therapy
prognosis
